| Zita rechiratidzo | ActiTide-AH3 |
| CAS Nha. | 616204-22-9 |
| INCI Zita | Acetyl Hexapeptide-8 |
| Application | Lotion, Serums, Mask, Facial cleanser |
| Package | 100g / bhodhoro, 1kg / bhegi |
| Chitarisiko | Hupfu hwakachena kusvika kuchena |
| Solubility | Mvura inonyungudika |
| Function | Peptide series |
| Sherufu hupenyu | 2 years |
| Storage | Chengetedza mudziyo wakavharwa zvakasimba munzvimbo inotonhorera, yakaoma pa2 - 8°C. |
| Dosage | 0.005-0.05% |
Application
Tsvagiridzo yemaitiro akakosha ekurwisa kuunyana kwakatungamira mukuwonekwa kweActiTide-AH3, hexapeptide yekuvandudza yakagadziridzwa kuburikidza nenzira yesainzi kubva pakugadzira kwakadzikama kusvika pakugadzirwa kweGMP, ine mhedzisiro yakanaka.
ActiTide-AH3 inopa kuunyana-kuderedza kushanda kwakafanana neBotulinum Toxin Type A, uku ichidzivirira njodzi dzejekiseni uye ichipa zvakanyanya mutengo-kubudirira.
Cosmetic Benefits:
ActiTide-AH3 inoderedza kudzika kwekukwinya kunokonzerwa nekutsikirira mhasuru yechiso, ine mhedzisiro yehuma uye periocular wrinkles.
Mechanism of Action:
Tsandanyama contraction inoitika neurotransmitter inoburitswa kubva kune synaptic vesicles. Iyo SNARE yakaoma - musangano weternary weVAMP, Syntaxin, uye SNAP-25 mapuroteni - yakakosha kune vesicle docking uye neurotransmitter exocytosis (A. Ferrer Montiel et al., JBC 1997, 272: 2634-2638). Iyi yakaoma inoita seya cellular hook, inobata vesicles uye kutyaira membrane fusion.
Sechimiro chemimetic cheSNAP-25 N-terminus, ActiTide-AH3 inokwikwidza neSNAP-25 yekubatanidzwa muSNARE yakaoma, ichigadzirisa gungano rayo. Destabilization yeSNARE yakaoma inokanganisa vesicle docking uye inozotevera neurotransmitter kuburitswa, zvichitungamira kuderedzwa kwemhasuru kudhonzwa uye kudzivirira kwekuwonyana uye mutsara kuumbwa.
ActiTide-AH3 inzira yakachengetedzeka, ine mari yakawanda, uye yakapfava kune Botulinum Toxin Type A. Inonangana nepamusoro penzira imwe chete yekuwunyana asi inoshanda nemuchina wakasiyana.
