Trade name | UniAPI-PBS |
CAS | 1405-20-5 |
Product Name | Polymyxin B sulfate |
Chitarisiko | Muchena kana hupfu huchena |
Solubility | Mvura inonyungudika |
Application | Mushonga |
Assay | Huwandu hwepolymyxin B1, B2, B3 uye B1-I: 80.0% minPolymyxin B3: 6.0% maxPolymyxin B1-I: 15.0% max |
Package | 1kg net pagaba realuminium |
Sherufu hupenyu | 2 years |
Storage | Chengetedza munzvimbo inotonhorera uye yakaoma, kure nechiedza. 2 ~ 8 ℃ yekuchengetedza. |
Mushonga Wemakemikari |
Application
Polyxin B sulfate ndeye cationic surfactant antibiotic, musanganiswa wepolyxin B1 neB2, inogona kuvandudza kupenya kwesero membrane. Zvinenge zvisinganhuhwi. Sensitive to light. Hygroscopic. Soluble mumvura, zvishoma soluble mu ethanol.
Clinical effect
Iyo antibacterial spectrum uye kiriniki application yakafanana nepolymyxin e. ine inhibitory kana bactericidal madhara paGram-negative mabhakitiriya, akadai seEscherichia coli, Pseudomonas aeruginosa, paraescherichia coli, Klebsiella pneumoniae, acidophilus, pertussis uye dysentery. Kliniki, inonyanya kushandiswa hutachiona hunokonzerwa nehutachiona hwehutachiona, weti system hutachiona hunokonzerwa nePseudomonas aeruginosa, ziso, trachea, meningitis, sepsis, kupisa hutachiona, ganda uye mucous membrane utachiona, nezvimwe.
pharmacological chiito
Iine antibacterial effect paPseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus, enterobacter, Salmonella, Shigella, pertussis, pasteurella uye Vibrio. Proteus, Neisseria, Serratia, pruvidens, Gram-positive bacteria uye obligate anaerobes vakanga vasina hanya nemishonga iyi. Pakave nekupokana pakati pemushonga uyu nepolymyxin E, asi pakanga pasina kupesana pakati pemushonga uyu nemamwe maantibiotic.
Inonyanya kushandiswa ronda, urinary turakiti, ziso, nzeve, trachea chirwere chinokonzerwa nePseudomonas aeruginosa nedzimwe Pseudomonas. Inogonawo kushandiswa sepsis uye peritonitis.